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Virtual Reality in Medicine:

A Survey of the State-of-the-Art

Executive Summary

John A Waterworth

Department of Informatics

Umeå University, Sweden

jwworth@informatik.umu.se


1. Introduction

Aims of this Survey

Outline the state-of-the-art

Make recommendations

Stimulate discussion and collaborative action.

3 target areas: surgery in general, neurosurgery, mental health

and 3 types of application: training, planning, treatment

(excluded: visualisation of records, architectural planning, robotics)


What is Medical VR?

Virtual Reality with a medical application:

Visualisation of data (usually anatomical)

Interaction with visualised data

Simulated behaviours of simulated realities:

increasingly as a result of interactions

"Realisation" in modalities other than vision:

sound, force, touch, smell


What is Medical VR?

The current status, pre-VR: 2D data slices:

Visible Human Slice Stacks - CT scans


2. Techniques Used in Medical VR

Virtual Realisation

Models have to be accurate for purpose:

training, planning, performing, therapy....

Tomography

CT (CAT)

MRI

Ultrasound

Physiological Imaging (PET, SPECT)

Range finders...


Virtual Realisation Techniques

Surface rendering of polygons - natural for graphics machines

But, extracting surface is not easy, and there are no insides!

Surface rendering - Visible Productions skull


Virtual Realisation Techniques

Hybrid models - with texture mapping

Immersive Body Parts - EVL eye - Surface model with texture mapping


Virtual Realisation Techniques

Hybrid models - with texture mapping

Boston Dynamics Reach-In Suture Trainer with texture mapping


Virtual Realisation Techniques

Volume rendering - natural form for volumetric data

needs alot of processing power, but is worth it!

Volume Rendering from MRI data - KRDL, Singapore


Virtual Realisation Techniques

Modelling objects - first stage of adding meaning

e.g. using atlases (e.g. VH),

Identifying the objects - Segmentation, labelling

Segmented and labelled, from VH data by KRDL, Singapore

Talairach and Tournoux Atlas (left) and Schaltenbrand and Wahren Atlas (right)


Virtual Realisation Techniques

Modelling objects - first stage of adding meaning

e.g. registration of multiple sources

When more than one image modality involved: Registration - Voxelman


Virtual Realisation Techniques

Modelling behaviours - autonomous, interactive and predictive

using physically-based modelling

How do objects behave?

Catheter simulation (da Vinci) from KRDL

A big advantage of object and behaviour simulation is that it allows prediction of outcomes, not just planning the interventions. For example, a face can be visualised after reconstructive plastic surgery to assess the appeal of the results.

Craniofacial surgery simulation from Erlangen Institute, Germany


Displays and Trackers

Head-mounted, CAVE, BOOM, PUSH immersion

Mechanically Tethered Displays: The BOOM, University of Illinois


Displays and Trackers

Head-mounted, CAVE, BOOM, PUSH immersion

The CAVE from EVL, University of Illinois


Displays and Trackers

Head-mounted, CAVE, BOOM, PUSH immersion

Responsive Workbench, from GMD, Germany


Displays and Trackers

Reflection-based "reach in" reality

(avoids hands in the way)

Reflection-based display - The Virtual Workbench, KRDL, Singapore

Reflection-based display - Boston Dynamics


Displays and Trackers

Gloves, Probes, Props, Joysticks

UC Berkeley Robotics Department Glove

University of Virginia "Props" Interface

Polhemus stylus probe


Displays and Trackers

Vibro- and Electro-tactile stimulation (simple surface texture)

Micro-pin stimulation (complex surface textures, and edges)

Pneumatic and force feedback (shape)

UC Berkeley, Robotics and Intelligent Machines Laboratory


Displays and Trackers

Force feedback (shape and response)

Currently cumbersome and coarse,

Used in endoscopy simulators

Force Feedback - SensAble`s PHANToM


Displays and Trackers

Force feedback (shape and response)

Force Feedback - Boston Dynamics

Immersion Laparoscopic Impulse Engine


3. Application Areas of VR in Medicine:

Surgery

Training: Simulators

Endoscopy, Open Surgery

Planning: Complex Data Visualisation

Neurosurgery, Radiosurgery

Performing: Augmented-Reality Surgery, Robotics

Collaborating: Telemedical Training, Planning, Performing


Training Simulators

PROBLEMS with current surgical training:

Training in OT increases risk and produces longer operations

New surgical procedures require training by other doctors,

usually busy with their own clinical work

Difficult to train physicians in rural areas in new procedures

Training opportunities for surgeons are on a case-by-case basis

Animal experiments expensive, anatomy is different

SOLUTION:

Training Simulators: Practice difficult procedures under computer control


Training Simulators

Advantages:

Training can be done anytime

Reduction of operative risk with new technology

Improves surgical morbidity and mortality

Challenges:

Transfer of skills from simulation to actual patient?

Faithfulness hard to achieve:

how good is a training system if is not like the real thing?

Certification?

New Developments:

Force feedback, modelling of soft tissue, sound feedback


Training Simulators

Boston Dynamics open surgery anastomosis trainer


Training Simulators

Endoscopic surgery - the current situation

Karlsruhe Endoscopic Surgery Trainer

The pictures above illustrate both the value of simulators for training procedures, but also their current weaknesses in terms of realism. To realistically simulate an operation, the method of interaction should be the same as in the real case (as with flight simulators). When this is not the case, the VR can serve as an anatomy educational system rather than a training simulation.


Training Simulators

Gatech: Endoscopic Surgical Simulator

These systems focus on training the surgeon in the use of particular medical devices, rather than on training a better awareness of general or specific patient anatomy.


Planning: Complex Data Visualisation

Neurosurgery is the main area

Interaction method need not be realistic

Data and patient registration must be accurate

(stereotaxis)

Multiple data sources can be fused

Reduces risk, increases accuracy and speed


Planning: Complex Data Visualisation

Radionics' Stereoplan - a 'pure' planning system


Planning: Complex Data Visualisation

University of Virginia "Props" Interface used in pre-operative planning

In pre-operative planning the interaction method need not be realistic and generally is not. The main focus is on exploring the patient data as fully as possible, and evaluating possible intervention procedures against that data, not in reproducing the actual operation. The University of Virginia "Props" interface illustrates this. A doll's head is used in the interaction with the dataset, without any suggestion that the surgeon will ever interact with a patient's head in quite this way.

KRDL VIVIAN: the Virtual Workbench used for stereotactic tumour neurosurgery planning

Of course, the simulation must be accurate. Given this, techniques developed for plannng can sometimes be applied to the prediction of outcomes of interventions, as in bone replacements or reconstructive plastic surgery. Such simulations can also help in training, and in communications between doctors and patients (and their families).


Performing: Augmented Reality Surgery

Blending the real and the virtual

Augmented Reality

University of North Carolina - Ultrasound data seen in HUD superimposed on real world


Performing: Augmented Reality Surgery

Currently more used for planning than performing

Images need to be intra-operative

Open CT, MR scans, ultrasound

Needs very accurate registration of real patient and data

Surgeons resistant to fusing data and reality

(degradation of direct view)


Performing: Augmented Reality Surgery

Combined neurosurgery planning and augmented reality from Harvard Medical School


Telemedical Collaboration

Surprisingly little used currently:

1 in 1000 radiograms, 1 in 2000 home visits

Saves time and money

Robotics more useful for precision and routine than remotely

(network delays, etc.)

Remote diagnostics a promising use of VR


Mental Health and Physical Rehabilitation Applications

Arguably, the most successful application area to date

Functional Assessment and Rehabilitation

(e.g. strokes, Alzheimer's disease)

Physical Rehabilitation

(e.g. disability coping, physical weakness)

Phobias and Body Image Distortions

(e.g. acrophobia, anorexia)

Pain Reduction and Hospitalisation Effects

(e.g. burn treatment, bed confinement)

Psychological Assessment and Psychotherapy


Mental Health and Physical Rehabilitation Applications

Acrophobia project - University of Michigan


Mental Health Applications

Ecologically valid, but safe reality

VR is sufficently realistic to elicit fear

But encounter (and fear) can be controlled

Physiological measures can control the display

Avoids over-stimulation

Also highly effective for biofeedback

Environment can be accurately and repeatably controlled

Automated, standardised tests

Performance can be accurately measured

Can capture data unavailable through traditional tests

Technical demands are tractable


Mental Health Applications

Detour: Brain Deconstruction Ahead by Rita Addison

"I have to find my way back to my brain.
But since the accident, it feels just like a black hole.
I'm lost without our connection.
My mind, my best friend is hurt.
I miss you, I know you're in there,
I won't abandon you." - R. Addison

Scene from Osmose by Char Davies

"by changing space, by leaving the space of one's usual sensibilities,
one enters into communication with a space that is psychically innovating...
For we do not change place, we change our nature."
- Gaston Bachelard, The Poetics of Space, 1964


4. Conclusions

Conclusions: Criteria for Recommendations

Existing strengths

Strong local need/interest

Not already over-researched (products available)

although products can be incorportated or enhanced

Topics to Avoid:

Robotics, simple endoscopy, augmented reality


Conclusions: Our Assets

Strong graphics and simulation skills and machines

Surgery training and telemedicine needs

Neurosurgery, Dentistry and Odontology, Radiology

Mental and physical rehabilitation and therapy

Expertise in IT applications, including distance education and HCI


Conclusions: Observations

A hard problem is soft tissue

Another is collaboration:

between medics, programmers and HCI/HF people

Users must be involved in design

User trials are essential

The application areas must be important:

make a big difference, save money, and make us famous


Conclusions: Recommendations

Techniques:

1. Modelling of soft tissue - appearance and behaviour

2. Expansion of modalities - sound, force and haptics

3. Novel combinations of 1. and 2.

4. Holotropic realities - imaginative immersive worlds

Application Areas:

1. Educational systems and Neurosurgery planning

2. Training simulators

3. Enhanced Endoscopy and Remote diagnostics

4. Physical and Psychological therapeutics


Conclusions: Recommendations

Summary Table

Application Area Type of Outcome Scope of Research Primary Use
Surgery in General Specialised Devices (endoscopy) Expanded Modalities Training
+

Soft Tissues and Interactive Behaviours

+

Neurosurgery "Reach-In" Realities Increased Fidelity of Complex Structures Planning
Mental/Physical Health and Rehabilitation Immersive "Holotropic" Realities More Imaginative Realisations Treatment









Text (c) John Waterworth, Informatik, June1998

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